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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1914L1 |
BAM (8-22) acetate
BAM (8-22) acetate(412961-36-5 free base) |
Others | Others |
BAM (8-22) acetate 是脑啡肽原 A 的蛋白水解产物。BAM (8-22) acetate 可激活 Mas 相关的 G 蛋白偶联受体 (Mrgprs)、MrgprC11 和 hMrgprX1,并以 Mrgpr 依赖性方式诱导小鼠抓挠。 | |||
TP1914 |
BAM(8-22)
BAM (8-22) |
||
Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM); first isolated from bovine adrenal medulla. Unlike BAM 22P , does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03974 |
Bim Protein, Human, Recombinant (His)
BAM,BCL2-like 11 (apoptosis facilitator),B... |
Human | E. coli |
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L11 contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. BCL2L11 gene functions as an essential initiator of apoptosis in thymoc... |